What is the cause of high glutaminase?
In recent years, with the improvement of health awareness, more and more people have begun to pay attention to glutaminase indicators in liver function tests. Glutaminase (ALT and AST) is an important indicator of liver health, and abnormal values may indicate liver damage or other health problems. This article will analyze in detail the causes, symptoms and countermeasures of high glutaminase, and provide you with comprehensive answers based on the hot health topics on the Internet in the past 10 days.
1. What is glutaminase?

Glutaminase mainly includes alanine aminotransferase (ALT) and aspartate aminotransferase (AST), which are two important enzymes in liver cells. When the liver is damaged, these enzymes are released into the blood, causing elevated glutaminase levels in the blood. Therefore, high glutaminase is often an early sign of abnormal liver function.
| Glutaminase type | normal value range | primary source |
|---|---|---|
| Alanine aminotransferase (ALT) | 7-40U/L | liver |
| Aspartate aminotransferase (AST) | 13-35U/L | Liver, heart, muscle, etc. |
2. Common causes of high glutaminase
There are many causes of elevated glutaminase, the following are the most common ones:
| Cause classification | specific factors | Remarks |
|---|---|---|
| Liver disease | Hepatitis (viral, alcoholic), fatty liver, cirrhosis | Accounts for more than 70% of glutaminase elevations |
| drugs or toxins | Long-term use of antibiotics, antipyretics and analgesics, exposure to chemical toxins | Stop taking medication promptly and seek medical attention |
| Other diseases | Myocarditis, muscle damage, biliary obstruction | AST increases more significantly |
| living habits | Staying up late, drinking alcohol, eating high-fat foods | Can be improved by adjusting lifestyle |
3. The hot health topics on the Internet in the past 10 days are related to glutaminase
Combined with recent hot search data, the following topics are closely related to high glutaminase:
| Hot search topics | Related points | heat index |
|---|---|---|
| "Staying up late hurts the liver" | Staying up late for a long time leads to elevated liver enzymes | ★★★★☆ |
| "The impact of light fasting on the liver" | Extreme dieting may cause fatty liver disease | ★★★☆☆ |
| "Controversy over liver toxicity of traditional Chinese medicine" | Some Chinese medicines may cause liver damage | ★★★★★ |
4. Symptoms and countermeasures of high glutaminase
Mildly elevated glutaminase may have no obvious symptoms, but moderately or severely elevated glutaminase may cause the following symptoms:
1.Fatigue: Decreased liver metabolic function;
2.Loss of appetite: Digestive system affected;
3.Jaundice: Yellowing of the skin or whites of the eyes indicates severe liver damage.
Countermeasures:
1.Seek medical attention promptly: Check for causes such as hepatitis and fatty liver;
2.Adjust diet: Reduce greasy food and increase high-quality protein;
3.Stop drinking and limit drugs:Avoid alcohol and hepatotoxic drugs;
4.Regular review: Monitor glutaminase change trends.
5. Summary
High glutaminase is a warning sign of liver health and needs to be comprehensively judged based on lifestyle habits and medical examinations. In recent hot searches, issues such as staying up late, diet and drug hepatotoxicity have attracted much attention, further reminding the public to pay attention to liver function protection. If glutaminase abnormalities are found during examination, it is recommended to consult a professional doctor in time to avoid delaying treatment.
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